HEPARIN LITHIUM
Heparin Lithium
CAS: 9045-22-1
Molecular Formula: n.a.
HEPARIN LITHIUM - Names and Identifiers
HEPARIN LITHIUM - Physico-chemical Properties
| Molecular Formula | n.a. |
| Appearance | White solid |
| Storage Condition | +15C to +30C |
| MDL | MFCD00131308 |
| Use | Commonly used heparin anticoagulant, heparin sodium, potassium, lithium, ammonium salt, of which heparin lithium is the best |
| In vitro study | Heparin is a potent anticoagulant drug based on its ability to accelerate the rate at which antithrombin inhibits serine proteases in the blood coagulation cascade. Heparin interactes most tightly with peptides containing a complementary binding site of high positive charge density. Heparin resembles DNA as both are highly charged linear polymers that behave as polyelectrolytes. Heparin is believed to function as an anticoagulant primarily through its interaction with AT III by enhancing AT-III-mediated inhibition of blood coagulation factors, including thrombin and factor Xa. Heparin binds to AT III and thrombin in a ternary complex, increasing the bimolecular rate constant for the inhibition of thrombin by a factor of 2000. Heparin is principally located in the granules of tissue mast cells that are closely associated with the immune response. Heparin makes numerous contacts with both FGF-2 and FGFR-1 stabilizing FGF–FGFR binding. Heparin also makes contacts with the FGFR-1 of the adjacent FGF–FGFR complex, thus seeming to promote FGFR dimerization. |
HEPARIN LITHIUM - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36 - Wear suitable protective clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
| RTECS | MI0700000 |
| FLUKA BRAND F CODES | 3-10 |
| HS Code | 29319090 |
HEPARIN LITHIUM - Reference
| Reference Show more | 1. [IF=9.933] Donghai Li et al.Delivery of MiR335-5p-Pendant Tetrahedron DNA Nanostructures Using an Injectable Heparin Lithium Hydrogel for Challenging Bone Defects in Steroid-Associated Osteonecrosis.Advanced Healthcare Materials.2021 Nov 01 2. [IF=13.273] Donghai Li et al."Osteoimmunomodulatory injectable Lithium-Heparin hydrogel with Microspheres/TGF-β1 delivery promotes M2 macrophage polarization and osteogenesis for guided bone regeneration."Chem Eng J. 2022 May;435:134991 |
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Product Name: Heparin lithium Visit Supplier Webpage Request for quotationCAS: 9045-22-1
Tel: 18301782025
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Mobile: 18021002903
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Product Name: Lithium Heparin Request for quotation
CAS: 9045-22-1
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Mobile: 18971041571
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CAS: 9045-22-1
Tel: 18971041571
Email: vickyzhao@whdschem.com
Mobile: 18971041571
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